@Tyrano:
They make artificial devil fruits…
And I'm pretty sure the users introduced themselves as fruit users (Bian, Leo, Kabu).
Or at least there was no reference in them being uninformed about DF.
I know it's been answered already but let me make it clearer.
Kabu calling Robin's power as "Magic" and Leo referring to his powers as "Power".
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I know you mean this introduction but there's a difference from being introduced as having Devil Fruits and them actually knowing/saying they have Devil Fruits (it's even in parentheses).
Now that I think about it further, can anyone can confirm if we only get an introduction on Devil Fruits for Zoans? cause a lot of them can't talk.. usually it's in the dialogue right?
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Toy Soldier is the one who mentions Hobby Hobby Fruit, Usopp asks, Toy Soldier replies.
The rest is pretty much their attitude/dialogue towards known Devil Fruit users.
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About making SMILES.
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–- Update From New Post Merge ---
@RobZilla:
I'm gonna be honest, I'm gonna need to look back at all the previous references to Manshelly that we've seen over the course of the arc before I provide my take, they've been pretty spread out.
I'm 100% certain it's not gonna be another princess - ancient weapon scenario, though.
Yeah I don't think so either. Poseidon is a mermaid, ancient power of the seas, able to tame/control very large Sea Kings. Pluton is an ancient man-made battleship, to bring destruction and hell on earth. So Uranus should be something related to the sky and possibly not being a person nor made.
Of course we can't rule out the fact that there were rumors of Roger having one of the Ancient Weapons.
@Tyrano:
And the reason why Doflamingo came back to Dressrosa when his Donquixote family left several hundred years ago is still a mystery.
Recently Doflamingo told Bellamy that he wants to destroy the world. Manshelly might be his key.
I'm not saying you're wrong but the problem with this is that King Riku was the one who said he's sure Doflamingo wants her powers. Whether King Riku knows that Doflamingo wants to destroy the world or not, I'm not actually sure, but Doflamingo could use something to hide this incident, that's for sure.