Suddenly jumping into the thread, but anyway…-
http://www.nuzlocke.com/?page_id=2
Anyone partake in this? Honestly, its probably the only reason I'm playing HG right now. I received it a few weeks ago as a gift, grew bored of it after a few hours, and forgot about it. I doubt I would've given a second thought if I didn't happen to come upon this thing (the challenge, though the comic is great too). Like it says, it actually makes the game a lot deeper in that you actually appreciate the Pokemon you're sending into battle and using those you never would've given a thought to otherwise.
Since restarting the game, I'm preparing to go at Jasmine right now. I lost about two Pokemon to Whitney and Chuck respectively, but have found the game to be a helluva lot more enjoyable overall.