THQ announced on Monday that they would be producing not one, but two sequels to the Destroy All Humans franchise, both due out in early 2008.
http://wii.ign.com/articles/802/802458p1.html
The first game, Destroy All Humans: Big Willie Unleashed, was built from the ground up for the Nintendo Wii. Also being released on the Playstation 2 and Playstation Portable, Big Willie Unleashed will allow the player to control not only Crypto and his saucer, but also 'Big Willie', a large robot that is eeriely similar to the mascot of the 'Big Boy' restaurant chain.
http://xbox360.ign.com/objects/947/947060.html
The second game, Destroy All Humans: Path of the Furon, picks up where DAH: BWU leaves off. There is a threat to the Furon race, and Crypto must learn from a Furon martial arts guru in order to be able to stop it. He gains new powers, such as a psychic magnet, and the ability to freeze time. It will be available for the Playstation 3 and X-Box 360, and new features include downloadable content and online multiplayer.
Both games take place in the 1970's. Personally, I am really looking forward to the Wii game, and I hope to buy it once it is released.