We are rapidly approaching E3 2012's date of June 5th and as per Arlong Park tradition I'm opening the thread early so that everyone can begin their speculation.
We'll no doubt see footage of God of War: Ascension and the Last of Us from Sony, probably more Kinect nonsense from Microsoft, and of course Nintendo's press conference is most likely going to be almost entirely decided to the Wii-U which is reportedly going to release later this year and be renamed, the new name for the console will of course be introduced during their conference. Other than that another big thing to be looking out for is that Gabe Newell of Valve Software has stated that they will be announcing a game with a 3 in its title at this E3, but of course didn't say if it was Half-Life 3, Left 4 Dead 3, Portal 3, or Team Fortress 3.
I guess we'll see more of Resident Evil 6…? But I don't think that's really a big deal considering Xbox 360 owners who buy Dragon's Dogma is getting a playable demo a week before E3, not to mention the trailers have showed quite a bit of gameplay as well.