Big Mam is Lola's mom, as expected by many. She's been married 999 times because unlike her less successful in love daughter, men are usually too afraid of her to refuse her proposals, but then they always end up running away or getting killed. She was after Whitebeard to be her 1000th husband, but he perpetually refused and eventually also went and died before she could convince him.
Its weird but I could totally see this happening. That would be a funny twist to her character.