I always thought Doflamingo's family relationship was that of manipulation and a false kind of loyalty.
I mean, it fits with his puppet theme too.
I thought that was quite apparent in the snippets with Baby G and Monet's death.
Also I won't call them comrades as much as them, Trebol especially, spoiling the shit out of him.
But I get that the point is LoA does it better and is more of an authentic relationship.